Thursday, January 30, 2020
James Berardinelli. “Twelve Monkeys†Essay Example for Free
James Berardinelli. â€Å"Twelve Monkeys†Essay 12 monkeys Introduction            In the movie ‘12 monkeys’ there was a virus which was deliberately released in 1996 and killed more than five billion people. The survivors went to seek refuge into the underground sending volunteers to bring insect specimen from the universe to test for the virus presence. One of the sent prisoners is James cole who goes is given a chance to go back to 1996 but he is taken to 1990 instead. He remembers things as if he was in a dream. Among the things is where he remembers witnessing a man being killed in the airport while he was a child. This is what is always seen to be the Centre stage in whole movie (Lynette, 3). Below is a discussion on how mental illness can be judged on this particular movie for part one, part two discusses the definition of mental illness in regard to the social norms and believes, with part three closing with the discussion of how Coles experience relate to Platos allegory of the cave.            In this film, mental illness is featured in many instances for instance, when Jose mentions that the so called volunteers are said to go mad. This presents a clear show of mental illness in the movie. We also notice cole being locked up in the mental institution with other lunatics, showing that there were other many lunatics present. Goines is definitely crazy or schizoid because of his hallucinating and grandiosity nature. Dr. Railly, the psychiatrist alludes that may be the whole world may be insane. We really don’t understand if cole was really from the futureor was he ‘mentally divergent’. We notice cole questioning his mental capabilities, where he asks himself if it could not be great if he was crazy. Simultaneously the Dr. is convinced that he is from the furfure of which we know that this can not be right (Lynette, 8). If he was really sane and from the furfure, then how can one explain the voice that he hears, the one he calls bum calling him Bob, what of the changing guard faces what of the fact that he is never seen coming or leaving and his memory lapses? We really can’t know the physical divergence he claims to have because one can’t explain his fore knowledge about the boy in the well. The appearances in the world War onephotos and the bullets in his leg. In short, this movie seems to be implying that we may not be mentally ill or weird than the world we live.            Relative to the social believes and norms, mental illness or abnormality can be seen as not being an exact process as it tends to focus on different individuals with different lines of thinking. This relies on different situations, behaviors and context to which the measurement is applied (Weinberger ,2001)            In defining abnormality, people from different societies and countries have varied ideas. Each and every culture has its own concepts of what it considers to be normal or abnormal. This can make us conclude that what is considered as abnormal in one society is not the same in other societies. So, there is no society which is mere superior than the other in their perception of mental illness or one society has got many mental disorders than the other (American Psychiatric Association. 2000).            If we look at the deviation from the norms, something or somebody can be considered abnormal if does not conform to what could be considered statistically abnormal. Those who focus on this aspect, only consider specific aspects. For instance, the intelligence quotient (IQ), the personal traits and their distribution. Asserting that a person is is abnormal in this aspect typically means that they deviate from the numeric average of a specific trait and behavior patterns.            The other mostly applied aspect in examining the mental illness of people is the deviation from the social norms. Naturally, some behaviors are considered as being not accepted in the society, but they can still be expected to be applied in certain situations. The majority of the population knows how to adjust and come along with these changes (Weinberger ,2001). The ones that contradict this are taken as abnormal or mentally ill on the extremes.            Also, a person is considered abnormal if he/she is not functioning correctly in that he or she may lack a full range of emotion and feelings and therefore his life is considered abnormal. These kinds of people can only be able to participate in only limited range of functioning lifestyle(American Psychiatric Association. 2000). Distress can also be used to gauge the mental illness capability of people as it could be an underlying mental problem.            Another aspect in the social norms definition of mental illness is the person’s association with others. If a person relation with others courses people to feel discomfort, it could be taken as these people are not mentally right. Along with this is the people’s unpredictable behavior which could much reflect on their mental health.            The Cole’s experiences relate to the Plato’s’ allegatory of the cave’ as his allegations that the real world may not be what our senses reveal. In relation to the Cole’s experience, we see him moving from one world of the past to the furfure or the vice varsa. In real this could only be a dream or mere imaginations, this alludes that Cole’s experiences could be reflecting Plato’s thoughts or allegations. In his Dialogue with Glaucon, we are not sure of the cave which he was referring to, either it could be the underground that the people had escaped to after the virus struck the universe or the prison where Cole was imprisoned.            When he imagined that the prisoners could think that the sound that they heard were really coming from the shadows, it coincides with Cole seeing the changing face of the guard and that of omnipresence. His concepts on the shadows could reflect Cole’s switching from one world to another. Was what he saw from the 1990 world true or could it his experience from the 1996 and 2035? Which was the truer experience?            On the last part of their discussion with Glaucon, he tells him that they, meaning the government, can not show any gratitude for the culture which they have never received. This could be reflecting the 12 monkeys who had released the virus that almost eliminated the human race according to the film. He said that with education on how to tackle issues, one will be able to defeat these ill minded people, reflecting Cole’s endeavors. References Roger Ebert (1996-01-05). 12 Monkeys.Chicago Sun-TimesLynette Rice (August 26, 2013). 12 monkeys pilot†. Entertainment Weekly James Berardinelli. Twelve Monkeys.Reviews Commission on Behavioral and Social Sciences Education, National Research Council. 2000. How People Learn: Brain, Mind, Experience, and School. Washington, DC: National Academies Press. Weinberger, D., Torrey, E.F., and Berman, K. 2001. Schizophrenia PET scan. Retrieved July 13, 2008 American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders, 4th Edition The Allegory of the Cave http://www.historyguide.org/intellect/allegory.html Source document
Wednesday, January 22, 2020
Down Syndrome Essay examples -- genetic disorder
Down syndrome is a genetic disorder in which a person is born with an extra copy of chromosome 21. There are three genetic variations that cause Down syndrome: Trisomy 21, Mosaic Trisomy 21 or Translocation Trisomy 21. There are many ways in which theses disorders affect the body.  Trisomy 21 occurs when an egg or sperm comes in with an extra copy of chromosome 21, then, once an embryo is formed and starts to develop, the chromosome is replicated in every single cell of the embryo. Trisomy 21 is the most common type of Down syndrome. About 92% of Down syndrome patients have this type. People with Trisomy usually have physical problems.      Mosaic Trisomy 21 happens when an egg or sperm come in with an extra copy of chromosome 21, then, once an embryo is formed and starts to develop, the chromosome is replicated in some of the cells. In Mosaic some cells have a normal number of chromosomes and some have an extra chromosome 21. Mosaic Trisomy 21 occurs in 2-3% of patients with Down syndrome. Mosaic Trisomy produces a wide range of possibility of a person having physical problems.      Translocation Trisomy occurs when the extra copy of chromosome 21 or a piece of chromosome 21 becomes attached to another chromosome. Usually the chromosome 21 attaches to chromosome 14. About 3-4% of patients with Down syndrome have Translocation Trisomy 21.      Anyone can be born with Down syndrome because it is a random event. Down syndrome is not usually inherited, but can be inherited... Down Syndrome Essay examples -- genetic disorder Down syndrome is a genetic disorder in which a person is born with an extra copy of chromosome 21. There are three genetic variations that cause Down syndrome: Trisomy 21, Mosaic Trisomy 21 or Translocation Trisomy 21. There are many ways in which theses disorders affect the body.  Trisomy 21 occurs when an egg or sperm comes in with an extra copy of chromosome 21, then, once an embryo is formed and starts to develop, the chromosome is replicated in every single cell of the embryo. Trisomy 21 is the most common type of Down syndrome. About 92% of Down syndrome patients have this type. People with Trisomy usually have physical problems.      Mosaic Trisomy 21 happens when an egg or sperm come in with an extra copy of chromosome 21, then, once an embryo is formed and starts to develop, the chromosome is replicated in some of the cells. In Mosaic some cells have a normal number of chromosomes and some have an extra chromosome 21. Mosaic Trisomy 21 occurs in 2-3% of patients with Down syndrome. Mosaic Trisomy produces a wide range of possibility of a person having physical problems.      Translocation Trisomy occurs when the extra copy of chromosome 21 or a piece of chromosome 21 becomes attached to another chromosome. Usually the chromosome 21 attaches to chromosome 14. About 3-4% of patients with Down syndrome have Translocation Trisomy 21.      Anyone can be born with Down syndrome because it is a random event. Down syndrome is not usually inherited, but can be inherited...
Tuesday, January 14, 2020
Youth Outpatient Hiv Depression Care Health And Social Care Essay
Worldwide, HIV/AIDS and depression are the prima causes of disease load for immature people aged 10-24 old ages. ( 1 ) Young people aged 15-24 history for half of all new HIV infections worldwide. Every twenty-four hours, 6,000 immature people aged 15-24 old ages become septic with HIV, which is an dismaying tendency, since this is the largest young person coevals in history. ( 2 ) In sub-Saharan Africa, more than half of all new infections are among immature people, with misss being peculiarly affected and represent a higher proportion of reported HIV infections and reported AIDS instances among youth ages 13 to 19 than among any other age group. ( 3,4 ) Cases of HIV infection diagnosed among youth 13 to 24 could be declarative of overall tendencies in HIV incidence because this age group has more late initiated bad behaviors. ( 5 ) Regular attending at clinical centres is required for HIV infection to supervise disease patterned advance, to get down and so supervise the response to antiretroviral therapy, and to give of import information to the patient on minimising the hazard of transmittal. Despite this demand for regular monitoring, loss to follow up in HIV cohort ( surveies ) can be a common happening and is infrequently reported. ( 6 ) This current survey purposes to find a ) the incidence of loss to follow up among HIV infected youth accessing attention at a youth- focused and a family- centered clinic in Kisumu, Kenya ; B ) baseline socio- demographic and clinical features associated with loss to follow up Justification: Nyanza Province in Kenya has the highest load of HIV infection in Kenya, with the HIV prevalence standing at 14.9 % , which is more than twice the national norm of 7.1 % . The national HIV prevalence amongst young person aged 15-24 old ages is 3.8 % ( 5.6 % in females and 11.4 % in males ) whilst that amongst 15- 19 twelvemonth olds is 2.3 % ( 3.5 % in females and 1.0 % in males. ) ( 7 ) In Kisumu City, the prevalence amongst females aged 15- 19 twelvemonth olds is 23 % , whilst in male childs of the same age class it is 3.5 % . ( 8 ) Merely a little proportion of these young persons were accessing attention and support services and keeping to care was low, with merely 5.3 % of patients enrolled at the HIV attention clinics within Kisumu City were aged 13-21 old ages. It has been shown that up to 60 % of immature people populating with HIV may non be in everyday HIV attention. Youth-centred HIV plans report that one of the most ambitious facets of working with HIV-positive young person is prosecuting them ab initio and retaining them in attention once they are enrolled. Despite the best attempts of outreach staff, lost-to-follow-up rates remain unwantedly high. ( 5 ) A major programmatic challenge for youth-specific HIV services is maintaining HIV-positive young person connected to care and back up systems that can run into their demands for emotional support, guidance, and bar instruction while supervising demands for medical attention, nutrition intercessions, and ARV intervention. ( 9 ) Adolescents with peri- natally-acquired HIV have alone features that may perplex their passage into adult-oriented attention scenes. ( 10 ) In one of a series of surveies on HIV and young person in Brazil, most doctors go toing advanced HIV preparation agreed th at the Ministry of Health should set up targeted services for HIV-infected young person. Nevertheless, associating HIV-infected striplings to HIV attention has proved hard. ( 11 ) The long-run nature of of HIV intervention calls for particular accent on keeping in attention of septic young person. ( 4 ) Transitioning the medical attention of kids with peri- natally-acquired HIV from paediatric attention to internal medical specialty patterns has become progressively of import as newer therapies prolong endurance.MethodsStudy DesignThis retrospective analysis used informations routinely collected from HIV infected patients enrolled in attention at Lumumba Health Center and at Tuungane Youth Center, both in Kisumu municipality. Patients aged between 15- 21 old ages enrolled into attention between July 2007 and October 2010 were eligible for inclusion in the analysis. The survey was approved by the institutional reappraisal boards of the Kenya Medical Research Institute and the Centers for Disease Control- KenyaProgram descriptionFamily AIDS Care and Education Services ( FACES ) , is a family- centered HIV bar, attention and intervention plan funded by the United States President ‘s Emergency Plan for AIDS Relief ( PEPFAR ) through a co-operative understanding with the Centers for Disease Control ( CDC ) . FACES- Nyanza provides these services in more than 60 government- tally wellness installations across 6 territories in Nyanza state of Kenya. Tuungane Youth Center is a youth- specific plan run by Impact Research Development Organization and is funded by PEPFAR to supply VCT, ABY and STI showing and intervention to youth aged between 13- 21 old ages. It is based within Kisumu municipality, Nyanza, Kenya. In Nov 2005, these two plans collaborated with the purposes of bettering HIV services to the young person accessing attention at the two sites. Care at the two sites is standardized, with the same clinical visit/ brush signifiers and attention is offered, free of charge, harmonizing to standardised national guidelines. There is besides a clinical staff exchange plan between the two sites. To day of the month, FACES- Lumumba has enrolled xx.xxx patients ( x % youth aged between 13- 21years ) while Tuungane has enrolled xxxx HIV infected patients since the coaction began.Missed assignments and defaulter tracingFaces, through its Clinic and Community and Health Assistants ( CCHA ) section, runs an active defaulter following programme to better patient keeping. Upon registration, each patient ‘s reference and contact information is recorded. A patient losing his/ her assignment is identified from the day-to-day attending registry and sought 3 yearss after a lost assignment. This same defaulter following mechanism is in topographic point at Tuungane.Data aggregationSocio-demographic, clinical and pharmacological informations collected at each patient ‘s visit on a standardised clinical visit signifier is manually entered into an electronic medical records system that was launched at both sites in July 2007. FACES manages the database.VariablesThe primary result is loss to follow up ( LTFU ) , defined as a patient losing their last assignment by & gt ; 4 months. Socio-demographic and clinical features considered as independent forecasters of LTFU and analyzed as binary/ index variables were baseline: age, above or below the population survey mean ; gender, male or female ; marital/ civil position, married/ partnered or non and clinic type ; youth- specific vs. family- oriented. Highest educational degree attained was categorized into 4: â€Å" none †, â€Å" some primary †, â€Å" some secondary †and â€Å" some college/ university †. CD4 was categorized into 4 classs of: â€Å" & lt ; 50cells/mm3 †, â€Å" 50-100cells/mm3 †, 100-200cells/mm3 †and â€Å" & gt ; 200cells/mm3 †WHO clinical presenting had phases I-IV. ART position at LTFU was analyzed as a binary variable, of all time started vs. ne'er started on ART. Baseline was defined as up to 60 yearss upon registration. Patients transferred out of either clinic, or determined to hold died or withdrawn from attention were non considered as LTFU.Datas analysisChi- square ( I†¡2 ) trial was used to analyse the categorical variables and logistic arrested development was used to place factors associated with loss to follow up. Unadjusted and adjusted odds ratios ( ORs ) and the 95 % assurance intervals were calculated in the theoretical accounts. Kaplan- Meier method was used to gauge the incidence of LTFU, presented as events per 100 person- old ages, from day of the month of registration. The event day of the month of a LTFU was the day of the month of the last clinic visit in the records. Patients determined to hold been transferred out, withdrawn, or dead, informations was censored at their day of the month of last assignment or day of the month of decease if known. Datas on patients still in active attention at the terminal of the survey period was censored at the day of the month of their last clinic visit. Wilcoxon log- rank trial was used to compare survival curves. All analyses were performed utilizing STATA version 11/SE package ( StataCorp LP, College Station, USA )Consequences:Patient features:Over the 3-year period, 927 patients ( 79 % female, average age 20 old ages ) were identified to be eligible for inclusion in the information analysis. 63 % were enrolled at the youth- specific clinic and a bulk ( 66 % ) of those who had their educational province indicated ( n=837 ) , had attained some signifier of primary school instruction while merely 1.7 % had non accompanied school at all. 61.5 % were non married/ partnered and 5.9 % were reported to hold some signifier of employment. Majority of the patients were of good clinical and immunological position ( 81 % were WHO phase I & A ; II and 80 % had CD4 cell counts & gt ; 200/mm3 ) . Merely 3 % were WHO stage IV and 5 % CD4 cell counts & lt ; 50/mm3. 61 % of the patients had ne'er been started on ART. ( Table 1 )Loss to follow up:57.2 % of the patients were documented as LTFU ( 79.4 % female, 66.8 % at the youth- specific clinic, p 0.006 ) . A huge bulk of the patients were of good immunological and clinical position ( 81 % WHO phase I & A ; II and 82 % CD4 cell count & gt ; 200/mm3 ) and had ne'er been started on ART ( 75 % , P & lt ; 0.0001 ) . 54 % were above the survey population average age of 22 old ages. ( Table 1 ) There were a sum of 390 LTFU events over 743 person- old ages of follow up. The incidence of LTFU was 53.4 per 100 individual old ages. The average clip to LTFU was 1.6 old ages upon registration ( 95 % CI 1.5- 1.7 ) . The incidence was significantly higher in those who had ne'er started ART ( Log rank p 0.0047 ) ( Figure 1 ) Univariate logistic arrested development identified youth- specific site ( OR 1.46, 95 % CI 1.12- 1.91 ) and ART position ( OR 0.23, 95 % CI 0.18- 0.31 ) to be associated with LTFU. On multivariate logistic arrested development, merely ART position was associated with LTFU ( OR 0.28, 95 % CI 0.19- 0.41 ) . Gender, age, matrimonial position, educational degree, occupational position, WHO clinical phase and CD4 were all non prognostic of LTFU. ( Table 1 )Discussion:This survey shows that LTFU is really high among this vulnerable age group, more so at the youth- focused clinic. Youth go toing attention at a youth- specific clinic are 46 % more likely to acquire LTFU. This might intend that a family- focussed theoretical account of attention is better than the youth- focussed theoretical account but this might be because young person taking to go to the youth- focused clinic have different societal features that place them at higher hazard of LTFU compared to those go toing attention at the family- focused site e.g lower revelation position, higher stigmatisation, hapless household support. Surveies to measure differences in societal features between young person go toing attention at the youth- particular and the family- centered clinic are required. A cardinal determination of this survey is that being on ART protects against LTFU even after commanding for other factors, consistent with other similar surveies done in grownup populations elsewhere. ( 12, 13, 14 ) HIV infected young person who are good clinically and immunologically and therefore non measure up for ART may non see the ground to adhere to their follow up visits. They may merely so return to the clinic when their wellness deteriorates and are likely to remain in attention as they receive ART. This could besides intend that attachment guidance to those non on ART is hapless or that the really ill ( and therefore necessitate ART ) are taken to the family- focused clinic by their similarly HIV infected household members. Surveies have demonstrated that mortality and loss to follow up rates are higher in patients non on but eligible for ART. ( 13 ) High pre- ART loss to follow up and particularly in those with less advanced clinical phase raises concern, since they are likely to be engaged in hazardous sexual patterns. ( 12 ) Strategies to enable earlier start of ART and to advance keeping in attention are required. In this survey, 50 % of patients got lost at 1 twelvemonth and 7 months of registration. Time from induction of ART to loss to follow up was nevertheless, non determined. Surveies among big populations found that on norm, 21 % of HIV infected patients get lost from attention in the first six months after get downing ART and approximately 40 % of patients are lost at two old ages, with big fluctuation in keeping rates. ( 15 ) There is demand for intercessions that improve linkage to care and prioritise ART induction particularly for those with low baseline CD4 counts. ( 16 ) There was no association between LTFU and clinical/ immunological position and others have besides shown that more advanced HIV disease and the absence of clinical phase appraisal are strongly associated with the hazard of decease ; but non with no followup or a loss to followup in the first 6 months. ( 17 ) Sarah et al nevertheless, reveal low baseline CD4 counts and unemployment to be independently associated with being lost to follow up. ( 18 ) Employment position was non associated with LTFU in this survey From the database, merely 60 patients were identified as discontinued from attention ( 9 deceased, 48 transferred to other clinics and 3 withdrew from attention ) and were therefore non defined as LTFU. Surveies to look into the true results of all patients defined as LTFU are required, since they could fall into one of three classs: wholly out of attention, go toing attention at other installations or deceased ( 19 ) . Patients who do non return for followup at clinics supplying comprehensive HIV/AIDS attention require particular attending. This is peculiarly true where resources are limited and clinic tonss are high. ( 20 ) Patients non doing their assignments may hold stopped taking antiretroviral drugs, ensuing in high mortality ; or may hold transferred to another plan. In ART programmes in resource-limited scenes a significant minority of grownups lost to follow up can non be traced, and among those traced 20 % to 60 % had died. ( 15 ) Constitution of systems for monitoring and following loss-to-follow-up patients, and to implement schemes for bettering keeping in attention is required for all HIV clinics. ( 18 ) Study strengths and failings: The follow up period of three old ages and a ample population gives the survey some strength, though the findings would non be generalizable to the full population since it involved merely one family- focused and one youth- focused clinic in Kisumu, Kenya. The theoretical account used in this survey was a hapless forecaster of the result. Similar surveies elsewhere are warranted.Decision:Newer and advanced attacks to retain HIV septic young person in attention, even at young person specific clinics, are desperately required. In the interim, targeted guidance should be directed toward HIV infected youth non yet get downing ART.Recognitions:I ‘d wish to admit all staff and patients at FACES and Tuungane who made this survey possible and to my advisers at UCB for the huge support and valuable way in making this survey.
Monday, January 6, 2020
Ralph Waldo Emerson Essay - 1000 Words
Ralph Waldo Emersonamp;#9;amp;#9;amp;#9;amp;#9;amp;#9;amp;#9;amp;#9;I am writing this essay on the beliefs and thoughts of Ralph Waldo Emerson on the subjects of individuality, society, government, technology, and spirituality. amp;#9;I think that Emerson believes that every person should be as much as individual as they can. Be who you are on the inside, dont try to be like everyone else. Dont worry about fitting in, if someone is a real friend, they will like you for who you are, real friends wont dump you for being yourself. amp;#9;When Emerson says quot;Insist on yourself; never imitate.quot; he is saying that you should act like you are on the inside; dont try to be like someone else. Be your own person and strive†¦show more content†¦He tells us this in the quote quot;Speak your latent conviction, and it shall be the universal sense.quot; Everyone will be able to understand what you are going through in one way or another. amp;#9;Emerson really believes that society is bad, whichever way you look at it. Dont listen to what society has to say, do things on your own free will how you want to do them. amp;#9;Society tells you how to act, how to dress, how to look, and how to live. You should do things how you feel that they should be done, not how society tells you to do them. Emerson says that quot;Society everywhere is in a conspiracy against the manhood of every one of its members.quot; Most of the time societys views and your views will not coincide with each other. amp;#9;quot;I confess I am a little cynical on some topics, and when a whole nation is roaring patriotism at the top of its voice, I am fain to explore the cleanness of its hands and purity of its heart, I have generally found the gravest and most useful citizens are not the easiest provoked to swell the noise, though they may be punctual at the polls.quot; Here Emerson is saying that you should be suspicious when society tells you to be or act a certain way. Question why they are telling you to be or act this way. 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